Recent Development in Microbial Transformation

MICROBIAL TRANSFORMATION OF CHOLESTEROL BY MYCOBACTERIUM SMEGMATIS

Mycobacterium smegmatis PTCC 1307 (CIP 73.26) was used as a microbial agent to produce androsta-1,4-diene-3,17-dione (ADD) and androst-4-ene-3,17-dione, two useful precursors in the synthesis of steroid drugs. The side chain of cholesterol, as the substrate, was selectively cleaved in the presence of five enzyme inhibitors. An intermediate structure with intact side chain, cholest-4-ene-3-one, ...

Recent Development in Production and Biotechnological Application of Microbial Enzymes

Copyright © 2015 Noomen Hmidet et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Microbial enzymes are considered as a potential biocatalyst for several biotechnological applications. They are mainly characterized by their bi...

Recent Development in Control of Threileria annulata in Iran

Microbial transformation of albendazole.

Screening scale studies were performed to biotransform anthelmintic drug albendazole by using twelve bacterial strains representing six genera and five actinomycetes cultures. Among the cultures studied, Bacillus subtilis MTCC 619, Escherichia coli MTCC 118 and Klebsiella pneumoniae MTCC 109 could transform albendazole to one metabolite whereas, Enterobacter aerogenes NCIM 2695, Klebsiella aero...

Recent progress in microbial nanoscopy

How microbial cell walls are spatially organized and how they interact with their environment are important questions in current microbiology, which today are still largely unsolved owing to the lack of high-resolution probing techniques. This article surveys recent research carried out in the Dufrêne laboratory that substantially contributed to the growth of the exciting new field of microbial...